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Pr. Zhong-Yi Dong | Oncology | Best Researcher Award

Teacher at Universidade Federal do Oeste do Pará, China

Dr. Dong Zhongyi, born in August 1985, is an esteemed oncologist specializing in tumor radiotherapy. With over a decade of experience, he serves as Associate Chief Physician in the Department of Radiotherapy at Southern Hospital, Southern Medical University. He leads the lung cancer subspecialty group and mentors postgraduate students. Dr. Dong has received numerous accolades, including recognition in the “World’s Top 2% Scientists” (2024) and the “Guangdong Special Support Plan for Young Top Talents in Health.” His research contributions include over 20 high-impact publications and multiple national patents. He has been invited to present at international and domestic conferences and has secured major research grants. Dr. Dong actively participates in academic leadership, holding key positions in multiple professional medical committees in Guangdong, China. His work significantly advances the field of oncology, particularly in radiotherapy and immunotherapy for lung cancer.

Professional Profiles📖

ORwID

Education 🎓

Dr. Dong Zhongyi pursued his medical education at prestigious institutions, building a strong foundation in oncology and clinical medicine. He earned his Bachelor of Clinical Medicine from the University of South China, School of Medicine (2004-2009). This early training equipped him with essential medical knowledge and clinical skills. Following his undergraduate studies, he specialized further by obtaining a Master’s degree in Oncology (2009-2012) from Southern Hospital, Southern Medical University. During this time, he developed expertise in cancer treatment and research, particularly in radiotherapy and targeted therapies. Dr.Dong then advanced his academic journey with a Ph.D. in Oncology (2014-2017) from the Lung Cancer Research Institute, Guangdong Provincial People’s Hospital, under the mentorship of Professor Yilong Wu. His doctoral research focused on the molecular mechanisms of immune resistance and tumor microenvironments, providing critical insights into cancer progression and treatment strategies. This work laid the foundation for his impactful contributions to clinical oncology and translational medicine.

Work Experience💼

Dr. Dong Zhongyi has built a distinguished career in oncology, marked by extensive clinical practice, research, and teaching in tumor radiotherapy. He began his professional journey as a Resident Physician (2012-2014) at Xiangtan Central Hospital, Hunan Province, where he gained hands-on experience in patient care and medical oncology. This period helped him develop a strong clinical foundation in cancer treatment. Following this, he advanced to the role of Attending Physician (2017-2022) at Southern Hospital, Southern Medical University, where he further honed his expertise in lung cancer treatment and radiotherapy. His dedication to integrating research with clinical practice significantly improved patient outcomes. Currently, Dr. Dong serves as an Associate Chief Physician (2022-Present) at Southern Hospital, Southern Medical University, where he continues to lead advancements in oncology. In addition to his clinical role, he is deeply involved in medical education, serving as a Master’s Supervisor (2021-Present) and Doctoral Supervisor (2024-Present). Throughout his career, Dr. Dong has remained at the forefront of lung cancer research, pioneering innovative treatment strategies and leading multiple research projects. His commitment to mentoring young medical professionals has played a crucial role in shaping the next generation of oncologists

Awards and Honors 🏆

Dr. Dong Zhongyi has received numerous prestigious awards in recognition of his exceptional contributions to lung cancer research and oncology. He was honored with the “Guangdong Special Support Plan for Young Top Talents in Health,” reflecting his leadership in medical research. In 2024, he was listed among the “World’s Top 2% Scientists,” a testament to his global impact in oncology. His achievements in lung cancer research were further acknowledged when he ranked 41st among China’s Top 100 Schors in Lung Cancer (2022). Additionally, he received the IASLC Developing Nation Award twice, in 2016 and 2020, highlighting his contributions to international lung cancer research. In 2020, Dr. Dong was awarded the First Prize of the Guangdong Natural Science Award, recognizing his groundbreaking work in tumor radiotherapy and cancer treatment. His dedication to advancing oncology has also been supported by prestigious talent programs, including the “National Outstanding Young Scientist Cultivation Plan (Class A)” and the “Excllent Young Scientist Cultivation Plan” by Southern Medical University. These accolades underscore Dr. Dong’s remarkable impact on the field, cementing his status as a leading researcher and clinician in lung cancer treatment and translational medicine.

Skills💡

Dr. Dong Zhongyi is a distinguished expert in oncology research and clinical application, seamlessly integrating cutting-edge research into patient care. His expertise in radiotherapy and immunotherapy has contributed to advanced cancer treatment strategies, improving therapeutic outcomes. With a strong foundation in molecular and translational medicine, he continuously innovates in tumor biology, enhancing precision oncology approaches. As a prolific researcher, Dr. Dong has authored over 20 high-impact scientific papers, demonstrating his excellence in scientific writing and publishing. His commitment to academic mentorship is evident in his role as a supervisor for postgraduate research, nurturing the next generation of oncology professionals. Additionally, his contributions to medical innovation and patents—holding multiple invention patents—underscore his role as a leader in oncology research and education. Through these skills, Dr. Dong continues to drive advancements in cancer treatment and medical science.

Research Focus 🔬

Dr. Dong Zhongyi’s research encompasses both clinical and translational oncology, with a strong focus on advancing lung cancer treatment. His work in radiotherapy and immunotherapy has led to significant advancements in treatment strategies, improving patient survival and quality of life. He has extensively investigated the molecular mechanisms of immune resistance, shedding light on how tumor microenvironments influence therapy effectiveness. Additionally, Dr. Dong has contributed to understanding and mitigating the adverse effects of immunotherapy, developing strategies to enhance patient safety and treatment efficacy. His groundbreaking research has influenced global oncology guidelines and has been cited in expert consensus documents, underscoring his role in shaping the future of cancer care. By refining precision medicine approaches, his work continues to drive innovation in oncology, ultimately improving patient outcomes worldwide.

Conclusion✅

Dr. Dong Zhongyi is a highly deserving candidate for the Best Researcher Award. His groundbreaking contributions to lung cancer research, impressive publication record, and leadership in the oncology community make him a standout researcher. While expanding international collaborations and clinical impact could further enhance his profile, his achievements thus far position him as a strong contender for this prestigious recognition.

Publications Top Notes📚

 

CDK4/6 inhibition triggers ICAM1-driven immune response and sensitizes LKB1 mutant lung cancer to immunotherapy

Journal: Nature Communications

Year: 2023

PMID: 36871040

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PARP Inhibition Induces Synthetic Lethality and Adaptive Immunity in LKB1-Mutant Lung Cancer

Journal: Cancer Research

Year: 2023

PMID: 36512628

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Interstitial pneumonitis associated with combined regimen of immunotherapy and conventional therapies-pharmacovigilance database analysis with real-world data validation

Journal: BMC Medicine

Year: 2023

PMID: 36600276

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Splenomegaly in predicting the survival of patients with advanced primary liver cancer treated with immune checkpoint inhibitors

Journal: Cancer Medicine

Year: 2022

DOI: 10.1002/cam4.4818

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Organ-specific metastatic landscape dissects PD-(L)1 blockade efficacy in advanced non-small cell lung cancer

Journal: BMC Medicine

Year: 2022

PMID: 35410334

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Inferring Homologous Recombination Deficiency of Ovarian Cancer From the Landscape of Copy Number Variation

Journal: Frontiers in Oncology

Year: 2021

DOI: 10.3389/fonc.2021.772604

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Assessment of anti-PD-(L)1 for patients with coexisting malignant tumor and tuberculosis classified by active, latent, and obsolete stage

Journal: BMC Medicine

Year: 2021

DOI: 10.1186/s12916-021-02194-z

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De Novo Mutation in Non-Tyrosine Kinase Domain of ROS1 as a Potential Predictor of Immune Checkpoint Inhibitors in Melanoma

Journal: Frontiers in Oncology

Year: 2021

PMID: 34221982

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Efficacy and Treatment Strategies in Advanced Cancers with Liver Metastasis Receiving Atezolizumab Therapy

Journal: Cancer Management and Research

Year: 2021

PMID: 34135631

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Integrative evaluation of primary and metastatic lesion spectrum to guide anti-PD-L1 therapy of non-small cell lung cancer

Journal: Oncoimmunology

Year: 2021

PMID: 33996262

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Development and validation of a genomic mutation signature to predict response to PD-1 inhibitors in non-squamous NSCLC

Journal: Journal for ImmunoTherapy of Cancer

Year: 2020

DOI: 10.1136/jitc-2019-000381

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Development and interpretation of a pathomics-based model for the prediction of microsatellite instability in Colorectal Cancer

Journal: Theranostics

Year: 2020

DOI: 10.7150/thno.49864

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HPV-positive status associated with inflamed immune microenvironment and improved response to anti-PD-1 therapy in head and neck squamous cell carcinoma

Journal: Scientific Reports

Year: 2019

DOI: 10.1038/s41598-019-49771-0

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Combination of TMB and CNA stratifies prognostic and predictive responses to immunotherapy across metastatic cancer

Journal: Clinical Cancer Research

Year: 2019

DOI: 10.1158/1078-0432.ccr-19-0558

Citations: [Check Citation Data]

Strong Programmed Death Ligand 1 Expression Predicts Poor Response and De Novo Resistance to EGFR Tyrosine Kinase Inhibitors Among NSCLC Patients With EGFR Mutation

Journal: Journal of Thoracic Oncology

Year: 2018

PMID: 30056164

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VISTA expression associated with CD8 confers a favorable immune microenvironment and better overall survival in hepatocellular carcinoma

Journal: BMC Cancer

Year: 2018

PMID: 29720116

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Genetic and Immune Profiles of Solid Predominant Lung Adenocarcinoma Reveal Potential Immunotherapeutic Strategies

Journal: Journal of Thoracic Oncology

Year: 2017

PMID: 29127022

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EGFR mutation correlates with uninflamed phenotype and weak immunogenicity, causing impaired response to PD-1 blockade in non-small cell lung cancer

Journal: Oncoimmunology

Year: 2017

PMID: 29147605

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Potential Predictive Value of TP53 and KRAS Mutation Status for Response to PD-1 Blockade Immunotherapy in Lung Adenocarcinoma

Journal: Clinical Cancer Research

Year: 2017

PMID: 28039262

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Mixed Responses to Systemic Therapy Revealed Potential Genetic Heterogeneity and Poor Survival in Patients with Non-Small Cell Lung Cancer

Journal: The Oncologist

Year: 2017

PMID: 28126915

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Potential biomarker for checkpoint blockade immunotherapy and treatment strategy

Journal: Tumour Biology

Year: 2016

PMID: 26779629

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FAT10 promotes hepatitis B virus-related hepatocellular carcinoma progression via Akt/GSK3β pathway

Journal: Oncogene

Year: 2013

PMID: 23812429

Citations: [Check Citation Data]

 

Zhong-Yi Dong | Oncology | Best Researcher Award

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