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Dr. Yunlong Liu | Disease | Best Researcher Award

Lecturer at Tiangong university, China

Yunlong Liu is a Lecturer in Biochemistry and Molecular Biology at Tiangong University, where he also supervises Master’s students. Born in Chengde, Hebei Province in 1995, he completed his Ph.D. at China Agricultural University in 2023. His doctoral research focused on structural biology, particularly the molecular mechanisms of transcriptional regulation by nuclear receptors and transcription factors. Throughout his academic career, Liu has made significant contributions to the field of molecular biology, particularly in understanding protein-DNA interactions and transcriptional control. His work has led to the determination of seven crystal structures and the identification of potent nuclear receptor inhibitors. Liu has published as the sole first author in Nucleic Acids Research and co-authored papers in high-impact journals such as Cell Discovery and the Journal of Biological Chemistry. He has received numerous accolades, including the National Ph.D. Scholarship and Outstanding Doctoral Dissertation Award.

Professional Profiles📖

ORCID

Education 🎓

Yunlong Liu earned his Ph.D. in Biochemistry and Molecular Biology from China Agricultural University in 2023, where he developed an expertise in structural biology. His doctoral research, which focused on understanding the molecular mechanisms of transcriptional regulation by nuclear receptors, allowed him to publish groundbreaking work in the field of protein-nucleic acid interactions. Prior to his Ph.D., Liu completed his undergraduate studies with distinction and participated in the National Mathematical Modeling Competition, where he won a national second prize in 2016. His academic journey has been marked by excellence and determination, receiving various awards such as the National Ph.D. Scholarship and Outstanding Ph.D. Graduate honors. These accomplishments have laid a strong foundation for his current role at Tiangong University, where he continues to contribute to scientific advancements in molecular biology and biochemistry.

Work Experience💼

Yunlong Liu began his professional career as a Lecturer in Biochemistry and Molecular Biology at Tiangong University in August 2023, where he actively engages in teaching and mentoring students at the College of Life Sciences. Prior to this, Liu completed his doctoral research at China Agricultural University (2018–2023), where he made notable advancements in the structural understanding of transcriptional regulation. His research focused on the molecular interactions between nuclear receptors, transcription factors, and DNA, with his work leading to the determination of seven key crystal structures. Liu’s experience also includes chairing significant research projects funded by the National Natural Science Foundation of China, contributing to groundbreaking studies in molecular biology and structural biology. His extensive experience in research and leadership, combined with his expertise in structural biology, positions him as a respected figure in the academic community.

Awards and Honors 🏆

Yunlong Liu has received numerous prestigious awards and honors throughout his academic career, reflecting his outstanding contributions to the field of molecular biology. Notably, he was awarded the National Ph.D. Scholarship in 2022, ranking second in his college, recognizing his exceptional academic and research performance. He was also the sole recipient of the Outstanding Doctoral Dissertation Award at China Agricultural University in 2023, a testament to the groundbreaking nature of his doctoral research. In addition, Liu was honored as the Outstanding Ph.D. Graduate of his university in 2023. His undergraduate years were also marked by significant achievements, including winning the National Mathematical Modeling Competition’s Second Prize (2016) and receiving the National Inspirational Scholarship in 2016 and 2017. Liu’s accolades reflect his dedication to academic excellence, both in terms of research and academic performance, and his commitment to advancing the field of molecular biology.

Skills 💡

Yunlong Liu possesses a diverse set of skills in molecular biology, structural biology, and biochemistry. His expertise includes advanced techniques in X-ray crystallography, allowing him to determine high-resolution crystal structures of protein monomers, protein-protein complexes, and protein-DNA complexes. Liu is also proficient in molecular modeling, protein purification, and nucleic acid manipulation, which are essential skills for studying molecular interactions and transcriptional regulation. In addition, he has demonstrated leadership skills by chairing large-scale research projects funded by the National Natural Science Foundation of China and contributing to several high-impact research initiatives. Liu’s strong analytical skills are complemented by his ability to work in multidisciplinary teams, publishing in prestigious journals such as Nucleic Acids Research, Cell Discovery, and Journal of Biological Chemistry. His skills in experimental design, data analysis, and scientific writing further enhance his ability to make significant contributions to the field of molecular biology and biochemistry.

Research Focus 🔬

Yunlong Liu’s research primarily focuses on structural biology, particularly the molecular mechanisms underlying transcriptional regulation mediated by nuclear receptors and other transcription factors. His doctoral research explored the structural basis of how nuclear receptors interact with DNA and their role in gene expression regulation. Liu has also investigated protein-protein and protein-DNA interactions, providing critical insights into the regulatory mechanisms of human nuclear receptors such as TR2/TR4. His research has led to the determination of several crystal structures, revealing how these molecules contribute to cellular processes. Moreover, Liu has identified a nuclear receptor inhibitor with a 100-fold enhanced efficacy, which may have potential therapeutic applications. Liu’s ongoing research interests include structural and functional studies of various regulatory proteins and the molecular mechanisms of nucleic acid repair. His work aims to further the understanding of complex cellular processes and provide new directions for targeted therapies.

Conclusion✅

Yunlong Liu is a highly deserving candidate for the Best Researcher Award due to his groundbreaking contributions to structural biology and transcriptional regulation. His extensive publication record, leadership in major research projects, and recognition through prestigious awards demonstrate his excellence in the field. By continuing to expand his international collaborations and exploring interdisciplinary research, he has the potential to further elevate his scientific contributions, making him an excellent choice for this esteemed award.

Publications Top Notes📚

  1. “Structures of human TR4LBD-JAZF1 and TR4DBD-DNA complexes reveal the molecular basis of transcriptional regulation” (2023)
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  2. “Crystal structures of REF6 and its complex with DNA reveal diverse recognition mechanisms” (2020)
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  3. “Structural basis of nucleic acid recognition and 6mA demethylation by Caenorhabditis elegans NMAD-1A” (2024)
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  4. “Structures of MPND reveal the molecular recognition of nucleosomes” (2023)
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  5. “Structural insights into the interactions and epigenetic functions of human nucleic acid repair protein ALKBH6” (2022)
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Citations:

Years Active:

  • Dr. Liu has been actively contributing to the field of molecular biology and computational genomics from 2020 to 2024, with ongoing contributions to the scientific community.
Yunlong Liu | Disease | Best Researcher Award

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